Endocrine Abstracts

Introduction: Radioactive iodine (RAI) for Graves’ disease (GD) was reported to have specific immune effects. The ability of T and B lymphocytes to cooperatively interaction during the immune response may be impaired in GD patients eligible for RAI therapy. We aimed at investigating cellular subsets involved in functional activity of adaptive immunity cellsone month after RAI therapy in patients with GD.Materials and methods: Thirty-six women with G...

Background: Foxp3(+) regulatory T cells (Treg) play a leading role in developing immune tolerance through active suppression in Graves’ disease (GD). The influence of radioactive iodine therapy (RAI) on the differentiated fractions of Treg of GD patients is still poorly understood. Aim: To estimate the differentiated fractions of blood Tregs and the CD25 expression in patients with GD after RAI.Materials and Methods: In total,...